Selected Publications

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  • A tonically active neuron continuously drives mutually exclusive motor states at different timescales.
    Jun Meng, Tosif Ahamed, Bin Yu, Wesley Hung, Sonia EL Mouridi, Zezhen Wang, Yongning Zhang, Quan Wen, Thomas Boulin, Shangbang Gao, Mei Zhen
    bioRxiv (2022) — Show abstract
  • Confounds of using the unc-58 selection marker highlights the importance of genotyping co-CRISPR genes.
    Rawsthorne-Manning H, Calahorro F, G Izquierdo P, Tardy P, Boulin T, Holden-Dye L, O'Connor V, Dillon J.
    PLoS One (2022) — Show abstract
  • Functional analysis of a de novo variant in the neurodevelopment and generalized epilepsy disease gene NBEA.
    Boulin T, Itani O, El Mouridi S, Leclercq-Blondel A, Gendrel M, Macnamara E, Soldatos A, Murphy JL, Gorman MP, Lindsey A, Shimada S, Turner D, Silverman GA, Baldridge D; Undiagnosed Diseases Network, Malicdan MC, Schedl T, Pak SC.
    Molecular Genetics and Metabolism (2021) — Show abstract
  • A single-nucleotide change underlies the genetic assimilation of a plastic trait.
    Vigne P, Gimond C, Ferrari C, Vielle A, Hallin J, Pino-Querido A, El Mouridi S, Mignerot L, Frøkjær-Jensen C, Boulin T, Teotónio H, Braendle C.
    Science Advances (2021) — Show abstract
  • Mutation of a single residue promotes gating of vertebrate and invertebrate two-pore domain potassium channels.
    Ben Soussia I, El Mouridi S, Kang D, Leclercq-Blondel A, Khoubza L, Tardy P, Zariohi N, Gendrel M, Lesage F, Kim EJ, Bichet D, Andrini O, Boulin T.
    Nature Communications (2019) — Show abstract
  • CRELD1 is an evolutionarily-conserved maturational enhancer of ionotropic acetylcholine receptors.
    D’Alessandro M, Richard M, Stigloher C, Gache V, Boulin T, Richmond JE, Bessereau JL.
    Elife (2018) — Show abstract
  • Reliable CRISPR/Cas9 Genome Engineering in Caenorhabditis elegans Using a Single Efficient sgRNA and an Easily Recognizable Phenotype.
    El Mouridi S, Lecroisey C, Tardy P, Mercier M, Leclercq-Blondel A, Zariohi N, Boulin T.
    G3 (Bethesda) (2017) — Show abstract
  • Microtubule severing by the katanin complex is activated by PPFR-1-dependent MEI-1 dephosphorylation.
    Gomes JE, Tavernier N, Richaudeau B, Formstecher E, Boulin T, Mains PE, Dumont J, Pintard L.
    Journal of Cell Biology (2013) — Show abstract
  • Biosynthesis of ionotropic acetylcholine receptors requires the evolutionarily conserved ER membrane complex.
    Richard M, Boulin T, Robert VJ, Richmond JE, Bessereau JL.
    PNAS (2013) — Show abstract
  • Positive modulation of a Cys-loop acetylcholine receptor by an auxiliary transmembrane subunit.
    Boulin T, Rapti G, Briseño-Roa L, Stigloher C, Richmond JE, Paoletti P, Bessereau JL.
    Nature Neuroscience (2012) — Show abstract
  • Functional reconstitution of Haemonchus contortus acetylcholine receptors in Xenopus oocytes provides mechanistic insights into levamisole resistance.
    Boulin T*, Fauvin A*, Charvet C, Cortet J, Cabaret J, Bessereau JL, Neveu C.
    British Journal of Pharmacology (2011) — Show abstract
  • A neuronal acetylcholine receptor regulates the balance of muscle excitation and inhibition in Caenorhabditis elegans.
    Jospin M, Qi YB, Stawicki TM, Boulin T, Schuske KR, Horvitz HR, Bessereau JL, Jorgensen EM, Jin Y.
    PLoS Biology (2009) — Show abstract
MeLiS | CNRS UMR 5284 | INSERM U1314
Université Claude Bernard Lyon 1
Institut NeuroMyoGène
Faculté de Médecine - 3ème étage, aile D
8 avenue Rockefeller
69008 LYON
+33 4 26 68 82 82